Research database

This Research Database has been developed by HCPC Europe to create an overview of the available research in the field of patient-friendly and adherence packaging. The database is for all members of HCPC Europe. Members can register as a user to get access to the database. Is your organisation not a member yet? Then please register your organisation as a member or contact our Executive Director Ger Standhardt for more information.


Improving oral medication compliance with an electronic aid

Demographic trends indicate that populations in the U.S., Europe, and Japan are aging rapidly. As people age, they will seek more health-care services and ingest more oral medications. Poor compliance in taking medications is especially problematic in the elderly because of the changes in their metabolism, cognitive skills, and physical abilities. Simple devices, special packaging, and physical aids, while offering some improvement, do not appear able to answer this challenge. Drawbacks to such mechanical devices include their inability to accommodate multiple medications, their inability to remind patients when to take their medications, their inability to be easily reprogrammed for different dosage regimens, and their higher packaging costs. Electronic medication compliance dispensers, such as the MedMinder, appear to address many of these issues, but their true utility awaits definitive results from further development and clinical field trials.


RMAIS: RFID-based medication adherence intelligence system

There has been compelling evidence that outpatients, especially those who are elderly or taking multiple complexly scheduled drugs, are not taking their medicines as directed, leading to unnecessary disease progression, complications, functional disabilities, lower quality of life, and even mortality. Existing technologies for monitoring and improving drug adherence are either costly or too complicated for general patients to use. In this paper, we introduce the detailed design and the complete prototype of a marketable Radio-Frequency Identification (RFID)-based Medication Adherence Intelligence System (RMAIS) that can be conveniently used at a residential home by ordinary patients. RMAIS is designed to maintain patients’ independence and enable them to take multiple daily medicine dosages of the right amount at the right time. The system is patient-centered and user-friendly by reminding a patient of the prescribed time for medication and dispensing it in a fully automatic and fool-proof way. This is achieved mainly due to its novel design of a motorized rotation platform and the smooth integration of a scale, an RFID reader, and the rotation platform. In addition, this system has an Internet-based notification function that is used to alert the patient when it is time to take medicine as well as report deviations from the prescribed schedule to the primary care physicians or pharmacists.


An in-home medication management solution based on intelligent packaging and ubiquitous sensing

A healthcare solution for medication noncompliance problem would help to save $177 billion annually in the United States. In addition, an in-home healthcare station (IHHS) is needed to meet the rapidly increasing demands for daily monitoring with on-site diagnosis and prognosis. In this paper, an intelligent medication management system is proposed based on intelligent package and ubiquitous sensing technologies. Preventive medication management is enabled by an intelligent package sealed by Controlled Delamination Material (CDM) and controlled by RFID link. Various vital parameters are collected by wearable biomedical sensors through the short range wireless link. Onsite diagnosis and prognosis based on these health parameters are supported by the scalable architecture. Additionally, friendly human-machine interface is emphasized to make it convenient for the elderly or disabled patients. A prototype system including the hardware, embedded software, user interface, database and some intelligent packages is implemented to verify the concepts.